Outcomes in Health-Related Quality of Life and Impact of Urinary Incontinence on Health-Related Quality of Life 7 Years After Robot-Assisted Radical Prostatectomy
- urologyxy
- Mar 8
- 2 min read
Objective:
We evaluated the long-term outcomes in health-related quality of life (QOL) after robot-assisted radical prostatectomy (RARP) and the factors influencing them.
Methods:
Overall, 246 patients who underwent RARP were included. The Expanded Prostate Cancer Index Composite (EPIC) and Short Form-8 (SF-8) questionnaires were utilized. Continence was defined as a score of ≤ 1 on question 1 of the International Consultation on Incontinence Questionnaire-Short Form. Questionnaires were collected preoperatively until 84 months postoperatively. For EPIC, each score was compared to preoperative values to examine the changes in HRQOL. For SF-8, the change in each score was examined separately for groups with and without urinary incontinence. Furthermore, factors influencing the SF-8 scores at 60 and 84 months postoperatively were analyzed.
Results:
In EPIC urinary function, urinary incontinence, and sexual function scores decreased significantly beginning from 1 month postoperatively and did not return to preoperative levels even after 84 months. In SF-8, social function, mental health, and mental health summary scores were significantly lower postoperatively in those with urinary incontinence. Multivariate analysis showed that urinary incontinence was a significant factor that affected the SF-8 scores at 60 and 84 months postoperatively (p = 0.003 and p = 0.039, respectively).
Conclusions:
The QOL related to urinary and sexual function showed a sustained decline up to 84 months postoperatively compared to preoperative levels. Urinary incontinence was a significant predictor of HRQOL at 60 and 84 months postoperatively.
Kimura Y, Honda M, Yamane H, Shimizu R, Nishikawa R, Yamaguchi N, Morizane S, Hikita K, Takenaka A. Outcomes in Health-Related Quality of Life and Impact of Urinary Incontinence on Health-Related Quality of Life 7 Years After Robot-Assisted Radical Prostatectomy. Int J Urol. 2025 Feb 27. doi: 10.1111/iju.70025. Epub ahead of print. PMID: 40012528.
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