Abstract Aims To evaluate the clinical and economic value of onabotulinumtoxinA (onabotA) vs oral pharmacotherapies for adults with OAB inadequately managed with anticholinergics from a United States (US) Medicare + societal perspective over 1 year. Materials and methods A Markov model-based 1-year cost per responder (CPR) analysis was conducted for patients achieving complete response (100% reduction in urinary incontinence episodes [i.e. complete dryness]). Comparators incl

ABSTRACT Objective To examine population-based trends in utilization of minimally invasive therapies (MITs) for overactive bladder (OAB) stratified by age and frailty among Medicare beneficiaries. Methods This population-based study used a 20% sample of fee-for-service Medicare beneficiaries to investigate rates of utilization for MIT for OAB [onabotulinumtoxinA injections (BTX), percutaneous tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM)] from 2015 to 2020

Abstract Introduction: The assessment of neurogenic lower urinary tract dysfunction (NLUTD) should include objective and quality of life (QoL) measures, considering sex and gender differences. Thus, we investigated the sex-specific impact of NLUTD on QoL. Methods: We evaluated consecutive outpatients with chronic NLUTD, who had completed the Short Form (SF)-Qualiveen questionnaire from September 2024 to January 2026 at a specialized spinal cord injury center, in a cross-secti

Abstract Purpose: To assess correlations between changes in urinary or bowel incontinence and health-related quality of life (HRQOL) in people with spina bifida. Materials and Methods: Children (aged 8-17.9 years) and adults (aged 18-55) with spina bifida self-reported urinary and bowel incontinence (clinic questionnaires) and HRQOL (validated QUALAS questionnaire) 3 to 24 months apart (2018-2024). Mixed effects linear regression was used to analyze changes in HRQOL correctin

Abstract Background Drug resistance is a crucial issue in patients with urinary tract infection (UTI). This study aimed to detect drug-resistant (DR) UTI cases using suitable machine learning classifiers for early prediction of DR UTI. Methods Three databases were used. The first database was from UTI patients at Alexandria University Hospital in Egypt. The second database was from a general clinic in Northern Mindanao, Philippines. The third was from Al-Rafa Laboratory, IBB

Abstract Purpose No information exists regarding the association between incontinence product use and men’s quality of life (QOL). Therefore, this study aimed to provide the first comprehensive assessment of how incontinence products relate to adult men’s well-being. Methods Data were obtained from the 2023 Japan Community Health Survey, a nationwide survey of 6210 adults (3122 men, 3088 women). Incontinence products included adult diapers and pads. The primary outcome was th

Abstract PURPOSE Continuity of care has been associated with lower health care use and costs. When general practitioners (GPs) serve as gatekeepers to hospital care, having an ongoing relationship with a GP may promote more efficient care and reduce urgent referrals, thereby lowering costs. We examined the association of 2 conceptually distinct measures of continuity in general practice with both urgent hospital admissions and hospital costs. METHODS We conducted a retrospect

Abstract Background: Spinal meningiomas (SM) are generally benign tumours with favourable surgical outcomes. However, their potential to impair sphincter function-particularly bladder control-remains insufficiently investigated. Bladder dysfunction, ranging from urge incontinence to complete urinary incontinence, may significantly impair quality of life and correlate with both neurological status and surgical outcomes. Objective: This study aimed to determine whether preopera

Abstract We evaluated the impact of chronological age on early urinary continence recovery following robot-assisted radical prostatectomy (RARP) using EPIC-26 and quantified discordance between patient-reported and surgeon-assessed continence. A total of 144 consecutive patients underwent RARP and were stratified into Group A (< 70 years, n = 74), Group B (70–<75 years, n = 36), and Group C (≥ 75 years, n = 34). Continence was assessed using EPIC-26 and independent surgeon ev

Abstract Morbid obesity (body mass index (BMI) ≥40 kg/m² or ≥35 kg/m² with comorbidities) predisposes patients to multiple urological disorders, including urinary incontinence, overactive bladder, erectile dysfunction, hypogonadism, nephrolithiasis, obesity-related kidney disease, renal cell carcinoma, and aggressive prostate cancer. Bariatric surgery is the most effective durable treatment for severe obesity. Glucagon-like peptide-1 receptor agonists, including semaglutide a

ABSTRACT Objectives To evaluate real-world biochemical recurrence-free survival (BCRFS) after radical prostatectomy (RP) for prostate cancer in Japan using nationwide data from the National Clinical Database (NCD). Methods This study included patients who underwent RP between April and December 2018 and were registered in the NCD from 647 participating institutions. BCRFS was estimated using the Kaplan–Meier method. Outcomes were evaluated according to surgical approach and..

ABSTRACT Aim This study aimed to identify demographic and clinical factors associated with advanced-stage pressure injury (PI) classification among hospitalised patients diagnosed with PIs using the Health Insurance Review and Assessment Service (HIRA) patient sample database. Design This secondary data analysis was approved by the Institutional Review Board of K University (IRB No. 2020-0266). Public data were analysed using SAS Enterprise Guide on a designated computer, and

Excerpt Urinary incontinence, defined by the International Continence Association as any involuntary leakage of urine, significantly affects patients' quality of life worldwide and poses a substantial global economic burden. In women, this condition exceeds 60% during their lifetime, with a higher incidence among those who have had children and increasing with age. Types of urinary incontinence include stress, urge, overflow, and mixed incontinence, each with distinct and som

Urinary Continence and Oncological Outcomes in Robot-Assisted Radical Prostatectomy (RARP) Background In robot-assisted radical prostatectomy (RARP), surgical techniques focus on preserving urinary continence. Methods like bladder neck preservation, nerve sparing, and dorsal venous complex (DVC) preservation aim to enhance postoperative quality of life. However, the question remains: does prioritizing functional preservation compromise oncological outcomes? Methods We conduct

Frailty Decompensation in Older Adults: Risk Factors, an LVEF Cutoff and Urinary Incontinence Background Frailty is a core manifestation of geriatric syndromes. Its decompensated state is linked to adverse outcomes, yet standardized assessment criteria are lacking. Methods From January 2022 to June 2024, we prospectively enrolled 538 patients with geriatric syndromes. We assessed frailty with the Fried phenotype. We used ROC curve analysis to find the optimal left ventricul

Which Patients Benefit From Video Urodynamics (VUDS)? A Retrospective Study Why video urodynamics matters Urodynamics evaluates lower urinary tract function. Video urodynamics (VUDS) adds anatomic information through fluoroscopy. Fluoroscopy needs extra personnel, equipment and radiation precautions, but VUDS can be valuable in certain patients. Study objective This study identifies patient characteristics linked to abnormal fluoroscopy findings, so clinicians can select VU

Modern BPH Treatments: Relief, Risks, and Long-Term Outcomes Benign prostatic hyperplasia (BPH) is highly prevalent among older men, affecting up to 70% of men aged 60–69 and more than 80% of those over 70. The growing number of minimally invasive BPH treatments offers patients more choices, but selecting the best option remains challenging because long-term comparative data are limited. BPH Treatment decisions depend on prostate size and anatomy, symptom severity, expected b

ABSTRACT: Real-World Outcomes After Radical Prostatectomy in Japan Objectives The objective of this study is to evaluate real-world biochemical recurrence-free survival (BCRFS) after radical prostatectomy (RP) for prostate cancer in Japan. We utilized nationwide data from the National Clinical Database (NCD) to achieve this goal. Methods This study included patients who underwent RP between April and December 2018. These patients were registered in the NCD from 647 participat

Key Points Question What was the association between nursing home staffing and laws adopted during the COVID-19 pandemic that immunized nursing homes from tort liability for patient harms? Findings In this cohort study of 13 205 nursing homes, facilities immune from tort liability exhibited a 2.5% reduction (7.9 hours per day) in staff time per patient per day than nursing homes in states that did not grant tort immunity. Meaning Tort immunity was associated with decreased

The US military’s proposal for routine testosterone screening presents a unique opportunity to improve men’s health. However, translating policy into practice will require evidence-based screening, accurate diagnosis, appropriate patient selection and careful consideration of fertility, lifestyle factors and long-term monitoring. Mubarak, M., Modgil, V. Routine testosterone screening in military personnel: an opportunity for evidence-based implementation in men’s health. Nat