Modern BPH Treatments: Relief, Risks, and Long-Term Outcomes Benign prostatic hyperplasia (BPH) is highly prevalent among older men, affecting up to 70% of men aged 60–69 and more than 80% of those over 70. The growing number of minimally invasive BPH treatments offers patients more choices, but selecting the best option remains challenging because long-term comparative data are limited. BPH Treatment decisions depend on prostate size and anatomy, symptom severity, expected b

ABSTRACT: Real-World Outcomes After Radical Prostatectomy in Japan Objectives The objective of this study is to evaluate real-world biochemical recurrence-free survival (BCRFS) after radical prostatectomy (RP) for prostate cancer in Japan. We utilized nationwide data from the National Clinical Database (NCD) to achieve this goal. Methods This study included patients who underwent RP between April and December 2018. These patients were registered in the NCD from 647 participat

Key Points Question What was the association between nursing home staffing and laws adopted during the COVID-19 pandemic that immunized nursing homes from tort liability for patient harms? Findings In this cohort study of 13 205 nursing homes, facilities immune from tort liability exhibited a 2.5% reduction (7.9 hours per day) in staff time per patient per day than nursing homes in states that did not grant tort immunity. Meaning Tort immunity was associated with decreased

The US military’s proposal for routine testosterone screening presents a unique opportunity to improve men’s health. However, translating policy into practice will require evidence-based screening, accurate diagnosis, appropriate patient selection and careful consideration of fertility, lifestyle factors and long-term monitoring. Mubarak, M., Modgil, V. Routine testosterone screening in military personnel: an opportunity for evidence-based implementation in men’s health. Nat

ABSTRACT Aim This study aimed to identify demographic and clinical factors associated with advanced-stage pressure injury (PI) classification among hospitalised patients diagnosed with PIs using the Health Insurance Review and Assessment Service (HIRA) patient sample database. Design This secondary data analysis was approved by the Institutional Review Board of K University (IRB No. 2020-0266). Public data were analysed using SAS Enterprise Guide on a designated computer, and

Abstract Objectives: This study explored the lived experiences, challenges and coping strategies of Arab male patients with spinal cord injury (SCI) who rely on intermittent catheterisation (IC) to manage neurogenic bladder. Design: A descriptive qualitative approach was employed, with data analysed using a phenomenological framework. Setting: Rehabilitation Hospital, King Fahad Medical City, Riyadh, Saudi Arabia. Participants: Male patients with SCI undergoing rehabilitation

Purpose: We report the duration of response to UGN-102 treatment in patients with recurrent low-grade intermediate-risk nonmuscle-invasive bladder cancer (LG-IR-NMIBC) 24 months after achieving complete response (CR). Materials and Methods: ENVISION is an ongoing, multinational, single-arm, phase 3 study in patients with biopsy-proven recurrent LG-IR-NMIBC. Patients received 6 once-weekly intravesical instillations of UGN-102. Patients underwent cystoscopy, urine cytology tes

ABSTRACT Objective To define mild, moderate and severe symptom categories of the neurogenic bladder symptom score (NBSS) and NBSS-short form (SF), and to calculate the minimal clinically important difference (MCID) of the NBSS-SF. Methods We used existing datasets from the original NBSS validation study (n = 230 patients with spinal cord injury (SCI), multiple sclerosis, and spina bifida), and a large cross-sectional study of people with SCI (n = 1479) who completed the NBSS.

Abstract Introduction Differences in how Medicare advantage prescription drug plans (MA-PDs) and stand-alone prescription drug plans (PDPs) are financed may contribute to fewer coverage options for traditional Medicare beneficiaries. The Inflation Reduction Act (IRA) capped annual out-of-pocket spending and reduced government reinsurance, thereby placing more cost responsibility on plans and manufacturers and potentially further limiting coverage. Methods This study draws on

ABSTRACT Between 1994 and 2019, the number of treatments designated as ‘reasonable and necessary’ (R&N) for the treatment of an illness that had ever been developed increased from 1210 to 2845. We investigate the effect of R&N treatment growth on the mortality of Americans during the period 1999–2019. We employ a difference-in-differences (disease by year) research design: we measure attributes (the number and mean vintage) of the R&N treatments for a disease that had ever be

Abstract Microplastics (MPs), ubiquitous environmental pollutants, can enter the human body and exacerbate health risks. Polyvinyl chloride MPs (PVC-MPs) are emerging contaminants of particular concern due to direct clinical exposure pathway. However, the role of PVC-MPs in pathogenic bacterial infections remains poorly understood. Here, we investigate the role of PVC-MPs for the pathogenicity of uropathogenic Escherichia coli (UPEC), the primary causative agent of urinary tr

Abstract Purpose: Neurogenic bladder significantly impacts individuals after spinal cord injury. We hypothesized that there would be differences in bladder related symptoms and quality of life for 4 common bladder management methods. Materials and methods: In this prospective observational study we measured neurogenic bladder related quality of life after spinal cord injury. Study eligibility included age 18 years or greater and acquired spinal cord injury. Bladder management

Abstract Introduction: Urodynamic study (UDS) is a valuable diagnostic test in urological practice. Due to the nature of the test, patients may experience emotional and physical discomfort. Mixed information exists on the degree of emotional and physical discomfort and their association with age, sex, body mass index, prior explanation, use of clean intermittent catheterization (CIC), and presence of a neurogenic bladder. Methods: Over a period of 7 months, all patients under

Abstract Introduction: Recurrent benign prostatic obstruction (BPO) is a recognized complication following surgery. While Holmium laser enucleation of prostate (HoLEP) has been shown to be safe and effective as a salvage option after single procedure, outcomes in patients with multiple prior interventions remain poorly defined. This study aimed to evaluate the outcomes of HoLEP in patients with multiple prior BPO surgeries compared with surgery-naïve individuals. Methods: We

Abstract Background Minimally invasive surgical therapies for benign prostatic hyperplasia (BPH) are increasingly utilized but may have limited long-term durability, leading some patients to require re-treatment. Holmium laser enucleation of the prostate (HoLEP) is a size-independent option, but outcomes after prior BPH intervention remain incompletely characterized. We compared perioperative, postoperative, and functional outcomes of HoLEP in re-treatment versus treatment-na

Abstract Introduction: Urinary incontinence (UI)-including stress (SUI), urge (UUI), and mixed (MUI) subtypes-is associated with obesity, and weight loss is commonly recommended for intervention. However, the comparative effects of intentionality and weight loss strategies on UI severity remain poorly defined. Material and methods: We analyzed 16,331 adults from the 2001-2020 NHANES cohorts who self-reported 1-year weight loss and completed the UI questionnaire. Our use of a

Abstract Importance Tamsulosin is the most common treatment for lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (BPH). The ability of N-of-1 deprescribing trials to identify who may benefit from discontinuing chronic tamsulosin therapy is unknown. Objective To determine if N-of-1 deprescribing trials can identify older men who are receiving minimal benefit from tamsulosin therapy for LUTS. Design, Setting, and Participants Double-blind, plac

Abstract Background: Neurogenic bowel dysfunction is a frequent but often underrecognized problem in patients with multiple sclerosis (MS) and may contribute to disability and reduced quality of life. Objective: The aim of this study was to determine the prevalence and severity of bowel dysfunction in patients with MS using the validated Neurogenic Bowel Dysfunction (NBD) score and to evaluate its associations with urinary dysfunction, anxiety, depression, fatigue, cognitive

Abstract Background and Objectives: Primary central nervous system (CNS) demyelinating disorders such as multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), and seronegative longitudinally extensive transverse myelitis (LETM) frequently affect the autonomic nervous system (ANS). Comprehensive data across genitourinary, sudomotor, gastrointestinal, and sexual domains remain limited, e

Abstract Background PSA is not recommended for screening by The UK National Screening Committee due to risks of over-diagnosis and over-treatment. However, men in England aged 50+can request a PSA test from their GP. Aimes To investigate the association between PSA and cancer mortality and estimate the absolute and relative risk of prostate cancer deaths. Design & setting Nested case–control study using the Clinical Practice Research Datalink (CPRD) GOLD database. Method Cas