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Clinical and economic value of onabotulinumtoxinA vs oral pharmacotherapies in overactive bladder in the United States
Abstract Aims To evaluate the clinical and economic value of onabotulinumtoxinA (onabotA) vs oral pharmacotherapies for adults with OAB inadequately managed with anticholinergics from a United States (US) Medicare + societal perspective over 1 year. Materials and methods A Markov model-based 1-year cost per responder (CPR) analysis was conducted for patients achieving complete response (100% reduction in urinary incontinence episodes [i.e. complete dryness]). Comparators incl
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Trends in the Utilization of Minimally Invasive Therapies for Overactive Bladder Among Older Adults: A National Medicare Study
ABSTRACT Objective To examine population-based trends in utilization of minimally invasive therapies (MITs) for overactive bladder (OAB) stratified by age and frailty among Medicare beneficiaries. Methods This population-based study used a 20% sample of fee-for-service Medicare beneficiaries to investigate rates of utilization for MIT for OAB [onabotulinumtoxinA injections (BTX), percutaneous tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM)] from 2015 to 2020
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Sex-Specific Impact of Neurogenic Lower Urinary Tract Dysfunction on Quality of Life: A Cross-Sectional Study
Abstract Introduction: The assessment of neurogenic lower urinary tract dysfunction (NLUTD) should include objective and quality of life (QoL) measures, considering sex and gender differences. Thus, we investigated the sex-specific impact of NLUTD on QoL. Methods: We evaluated consecutive outpatients with chronic NLUTD, who had completed the Short Form (SF)-Qualiveen questionnaire from September 2024 to January 2026 at a specialized spinal cord injury center, in a cross-secti
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