Abstract Introduction: To determine whether prolonged urinary catheterization due to vesicourethral anastomotic leakage (VAL) after robot-assisted radical prostatectomy (RARP) impacts urinary continence recovery and quality of life (QOL). Methods: We retrospectively analyzed 360 patients who underwent transperitoneal RARP at a single institution from January 2022 to December 2024. All patients underwent cystography on postoperative day 6 or 7. Those with VAL requiring extende

Active surveillance (AS) is a common approach for men with low-risk prostate cancer, allowing them to avoid or delay surgery or radiation. Because some lab and observational studies suggested that metformin (a widely used diabetes drug) might slow cancer growth, researchers tested whether it could help men on AS stay progression-free longer. The Metformin Active Surveillance Trial (MAST) was a large, well-designed study involving 408 men with low-risk, localized prostate canc

Abstract Purpose Active surveillance (AS) is a standard management strategy for low-risk prostate cancer (PCa), but a significant proportion of patients ultimately experience disease progression. Metformin, a commonly prescribed antidiabetic agent, has demonstrated antitumor activity in preclinical studies and observational data, prompting investigation into its potential to delay PCa progression. Patients and Methods The Metformin Active Surveillance Trial (MAST) was a multi