Abstract Aims: Nocturnal enuresis (NE) and daytime urinary incontinence (DUI) are often associated with neurodevelopmental disorders (NDs). Among NDs, children with incontinence have a higher rate of developmental coordination disorder (DCD). It is not known if the associated deficits of neuromotor skills persist over time or if they are associated with treatment outcome. Therefore, the aim of the study was to examine the neuromotor skills in children with incontinence prospe

Abstract Background Guidelines recommend fluoroquinolones or cotrimoxazole for urinary tract infections in men (UTIm), but safety data in frail older patients remain limited. The aim of this study was to compare the tolerability of these antibiotics in UTIm patients over age 75 years. Methods This multicenter retrospective study included patients age ≥75 years who were hospitalized for UTIm in 8 hospitals and treated with oral fluoroquinolone or cotrimoxazole. Adverse events

Abstract Importance It has been proposed that grade group (GG) 1 prostate cancer should no longer be defined as cancer but as a precancerous condition. One argument raised by critics is this would decrease adherence with essential monitoring (active surveillance) and therefore lead to increased prostate cancer mortality. However, relabeling GG1 prostate cancer also reduces overdiagnosis and overtreatment, and given that these are the major disincentives to prostate-specific