New Treatment Option for Men with BPH Shows Long-Term Success

A recent study presented at the American Urological Association meeting showed encouraging long-term results for men with benign prostatic hyperplasia (BPH) and bothersome lower urinary tract symptoms (LUTS) treated with the Urocross Expander System. This temporary device is inserted into the prostate through the urethra and remains in place for six months before being removed during a standard cystoscopy.

In the Expander-2 trial, involving 240 men aged 45 years and older, participants experienced significant symptom relief. Six months after device removal, symptom scores improved by nearly 50%, and benefits continued to increase over 30 months. About 74% of men achieved at least a 30% reduction in symptoms.

Importantly, sexual function, including erectile and ejaculatory function, was preserved, and urinary incontinence symptoms also improved. Quality of life scores showed substantial and lasting improvement. Post-procedure pain was generally mild, and no serious device- or procedure-related complications were reported.

Most side effects were temporary and included mild discomfort, painful urination, blood in the urine, and urinary urgency. Researchers believe the temporary implant may “remodel” the prostate, providing durable relief without leaving a permanent device behind.

Bassett, M. (2026, May 18). Temporary prostatic urethra expander for BPH/LUTS shows durable results. MedPage Today. https://www.medpagetoday.com/meetingcoverage/aua/121313